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Dale Bartholomew Cooper [7] was a special agent of the Federal Bureau of Investigation who in was assigned to investigate the brutal murder of the popular high school student, Laura Palmer in the town of Twin Peaks , Washington. He ended up falling in love with the town and gained a great deal of acceptance within the normally tight-knit community. While trying to rescue Annie Blackburn , Cooper became trapped in a bizarre alternate reality known in local Native American legends as the Black Lodge. Meanwhile, an identical, evil " doppelganger " of Cooper, associated with the malicious spirit " BOB ," was released into the world, passing itself off as Cooper to his friends and colleagues. The real Cooper spent several decades wandering the Lodge, unable to find a way out. Upon exiting via an electrical outlet, Cooper, in a severe catatonic state, was mistaken for his tulpa Dougie Jones and spent several days ushered about as "Dougie" by his oblivious family and colleagues.
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SparkNotes: The Last of the Mohicans: Chapters III–IV

To generate energy efficiently, the cell is uniquely challenged to co-ordinate the abundance of electron transport chain protein subunits expressed from both nuclear and mitochondrial genomes. How an effective stoichiometry of this many constituent subunits is co-ordinated post-transcriptionally remains poorly understood. Here we show that Cerox1 , an unusually abundant cytoplasmic long noncoding RNA lncRNA , modulates the levels of mitochondrial complex I subunit transcripts in a manner that requires binding to microRNAp. Increased abundance of Cerox1 cooperatively elevates complex I subunit protein abundance and enzymatic activity, decreases reactive oxygen species production, and protects against the complex I inhibitor rotenone. Cerox1 function is conserved across placental mammals: human and mouse orthologues effectively modulate complex I enzymatic activity in mouse and human cells, respectively. Cerox1 is the first lncRNA demonstrated, to our knowledge, to regulate mitochondrial oxidative phosphorylation and, with miRp, represent novel targets for the modulation of complex I activity. Converting food into energy requires many different proteins and cells control the relative amounts of the proteins in mitochondria to ensure this process is efficient.
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Complete this survey to tell us your thoughts on our site and help us make SparkNotes even better. See Important Quotations Explained. The narrator shifts the focus of attention from Magua and his party to another group of people in another part of the forest, a few miles west by the river. We meet the remaining primary characters: Hawkeye, a white hunter, and Chingachgook, his Mohican ally.
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Jones , is an American actor. He has arguably become best known for having played the title characters in the film Flash Gordon and in the short-lived TV series The Highwayman — Jones was born in Chicago , Illinois, and grew up in Sacramento , California.
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